Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Stages of Infection01:26

Stages of Infection

Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uncemented total knee arthroplasty is associated with higher complication rates: a propensity-matched retrospective study.

Archives of orthopaedic and trauma surgery·2026
Same author

A field polymerizing hydrogel enables simultaneous antimicrobial, hemostatic, and analgesic delivery in traumatic wounds.

Scientific reports·2026
Same author

Growth Plate Injuries: Advances and Future Directions in Regenerative Medicine.

Annals of biomedical engineering·2025
Same author

Harnessing MSC Immunomodulation in Orthopedics: Clinical Insights for Comorbidities.

Stem cell reviews and reports·2025
Same author

The Role of Arthroplasty in Acute and Failed Fracture Surgery Around the Hip.

Instructional course lectures·2025
Same author

The Role of Arthroplasty in Acute and Failed Fracture Surgery Around the Knee.

Instructional course lectures·2025

Related Experiment Video

Updated: Jun 9, 2026

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
14:05

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes

Published on: September 19, 2013

Infection.

Theodore Miclau1, Andrew H Schmidt, Joseph C Wenke

  • 1Orthopaedic Trauma Institute, San Francisco General Hospital, Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA 94110, USA. ortho.attending.ucsf.edu

Journal of Orthopaedic Trauma
|August 26, 2010
PubMed
Summary
This summary is machine-generated.

Musculoskeletal infections pose a significant healthcare challenge, especially with increasing implant-associated infections. This review covers recent advancements in understanding, diagnosing, and treating these complex conditions.

Related Experiment Videos

Last Updated: Jun 9, 2026

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
14:05

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes

Published on: September 19, 2013

Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Biomaterials Science

Background:

  • Musculoskeletal infections represent a major clinical and economic burden.
  • Post-surgical infection rates vary, with higher risks in severe trauma and with implant use.
  • Implant-associated infections are a growing global concern.

Purpose of the Study:

  • To review recent progress in the understanding of musculoskeletal infections.
  • To summarize current diagnostic approaches for musculoskeletal infections.
  • To outline contemporary treatment strategies for musculoskeletal infections.

Main Methods:

  • Literature review of recent scientific publications.
  • Synthesis of data on infection prevalence and risk factors.
  • Analysis of diagnostic techniques and treatment outcomes.

Main Results:

  • Infection rates are significantly higher in severe injuries and with orthopedic implants.
  • Advances in molecular diagnostics are improving pathogen identification.
  • Novel therapeutic strategies are emerging for implant-associated infections.

Conclusions:

  • Musculoskeletal infections, particularly those linked to implants, require ongoing research and improved management.
  • Early and accurate diagnosis is crucial for effective treatment.
  • Multidisciplinary approaches are essential for combating these challenging infections.