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Updated: Jun 9, 2026

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
Published on: September 28, 2022
Severe genital ulceration in an acute epstein-barr virus infection
Ghada N Al-Rawahi1, Simon R Dobson, David W Scheifele
1Department of Pathology and Laboratory Medicine, Vancouver, BC, Canada. ghada.al-rawahi@cw.bc.ca
Abstract:
Genital ulceration is a rare manifestation of infectious mononucleosis caused by Epstein-Barr virus (EBV). We report a girl with severe genital ulceration and tissue necrosis during primary EBV infection that required surgical debridement. The excised genital tissue was EBV polymerase chain reaction-positive whereas in situ hybridization was negative. This suggests that the ulceration was likely because of the inflammatory response to the virus and not because of the intense viral infection of the genitalia.
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