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Contemporary management of sinonasal cancer

K Thomas Robbins1, Alfio Ferlito, Carl E Silver

  • 1Division of Otolaryngology-Head and Neck Surgery, Southern Illinois University School of Medicine, Springfield, Illinois, USA.

Head & Neck
|August 26, 2010
PubMed
Abstract

Insights

Surgery remains the primary treatment for sinonasal cancer, offering the best outcomes despite modest survival rates for advanced stages. While treatment complications have decreased, improved therapeutic efficacy is still needed.

Area of Science:

  • Oncology
  • Head and Neck Surgery
  • Rhinology

Background:

  • Sinonasal cancer is a rare malignancy requiring specialized care from head and neck oncologists, rhinologists, and skull base surgeons.
  • Recent advancements in treatment modalities prompt an evaluation of their impact on patient outcomes.

Purpose of the Study:

  • To assess the effectiveness of current therapeutic strategies for sinonasal cancer.
  • To determine if recent innovations have improved treatment outcomes.

Main Methods:

  • A retrospective review of existing literature was performed.
  • Studies focusing on surgery, radiation, chemotherapy, and combined treatment approaches were analyzed.

Main Results:

  • Surgery is the preferred treatment, yielding the best results, though patient selection introduces bias.
  • Survival rates for advanced disease (T4 lesions) remain modest.
  • Complications associated with surgical and radiation therapy have been reduced.

Conclusions:

  • Enhanced treatment efficacy for sinonasal cancer is necessary.
  • Future research directions for therapeutic investigations are proposed.

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