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Environmental nitration processes enhance the mutagenic potency of aromatic compounds

Aurélie Bonnefoy1, Serge Chiron, Alain Botta

  • 1Laboratoire de Biogénotoxicologie et Mutagénèse Environnementale, EA 1784/FR 3098 ECCOREV, Faculté de Médecine, 27 Bd Jean Moulin, 13385 Marseille Cedex 5, France. aurelie.bonnefoy@univmed.fr

Environmental Toxicology
|August 26, 2010
PubMed
Summary

Aromatic nitration processes increase genotoxicity and mutagenicity. Nitro polycyclic aromatic hydrocarbons (PAHs) are environmental hazards, with 1-nitropyrene (1-NPy) and 1,8-dinitropyrene (1,8-DNPy) identified as potential human carcinogens.

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