Antifungal activities of some indole derivatives
Hui Xu1, Qin Wang, Wen-Bin Yang
1Laboratory of Pharmaceutical Design & Synthesis, College of Sciences, Northwest A & F University, Yangling 712100, PR China. orgxuhui@nwsuaf.edu.cn
Abstract:
Nine indole derivatives were evaluated in vitro against Fusarium graminearum, Alternaria alternata, Helminthosporium sorokinianum, Pyricularia oryzae, Fusarium oxysporum f. sp. vasinfectum, Fusarium oxysporum f. sp. cucumarinum, and Alternaria brassicae. Most of the compounds were found to possess antifungal activities. Especially compounds 2, 5, 8, and 9 exhibited broad-spectrum antifungal activities against the above-mentioned seven phytopathogenic fungi, and showed more potent activities than hymexazole, a commercial agricultural fungicide.
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