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Magnesium and insulin-dependent diabetes mellitus
1Department of Paediatrics & Child Health, Faculty of Medicine, University of Khartoum, Sudan.
Diabetes Research and Clinical Practice
|November 1, 1990
Summary
Magnesium deficiency is common in diabetes and linked to complications like heart disease and retinopathy. Supplementation may help, but more research is needed to confirm benefits for diabetic patients.
Area of Science:
- Endocrinology
- Metabolic Disorders
- Nutritional Science
Background:
- Diabetes mellitus is associated with micronutrient metabolism alterations.
- Magnesium deficiency (hypomagnesemia) is a prominent metal metabolism disturbance in insulin-dependent diabetes mellitus.
- Hypomagnesemia is implicated in both acute and chronic diabetic complications.
Purpose of the Study:
- To review the role of micronutrient metabolism changes in diabetes pathogenesis.
- To highlight the association between hypomagnesemia and diabetic complications.
- To discuss the potential benefits of magnesium supplementation in diabetes.
Main Methods:
- Literature review of studies on micronutrients and diabetes.
- Analysis of evidence linking magnesium levels to diabetic complications.
- Examination of potential therapeutic roles for magnesium supplementation.
Main Results:
- Magnesium deficiency is a significant finding in insulin-dependent diabetes mellitus.
- Hypomagnesemia is correlated with increased risk of ischemic heart disease and severe retinopathy in diabetics.
- Evidence suggests magnesium supplementation may normalize levels and mitigate vascular complications.
Conclusions:
- Altered magnesium metabolism plays a role in diabetes pathogenesis and complications.
- Hypomagnesemia is a critical concern in diabetic vascular complications.
- Further well-designed studies are required to establish the efficacy of magnesium supplementation for diabetic patients.
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