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The relationship between body weight, body condition, and survival in cats with heart failure
E Finn1, L M Freeman, J E Rush
1Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA 01536, USA.
Insights
In cats with heart failure, both very low and very high body weights are linked to shorter survival times. Intermediate body weight appears to offer the best prognosis for feline heart failure patients.
Area of Science:
- Veterinary Cardiology
- Feline Medicine
- Animal Health
Background:
- Obesity in human heart failure patients is associated with improved survival.
- The relationship between body weight and survival in cats with heart failure is not well understood.
Purpose of the Study:
- To investigate the association between body weight, body condition score (BCS), and survival in cats diagnosed with heart failure.
- To determine if body weight or BCS can predict survival outcomes in feline heart failure.
Main Methods:
- A retrospective study of 101 cats with International Small Animal Cardiac Health Council (ISACHC) heart failure classes II, IIIa, or IIIb.
- Data collected included initial body weight, BCS, body weight changes, and survival times.
- Survival analysis was performed using a model incorporating initial body weight and survival to discharge.
Main Results:
- Median initial body weight was 5.1 kg, and median BCS was 5.
- Survival time for all cats was 93 days.
- A model combining initial body weight (and its square) and survival to discharge significantly predicted overall survival (P<.0001).
Conclusions:
- A U-shaped relationship exists between body weight and survival in cats with heart failure, with lowest and highest weights associated with reduced survival.
- Body weight is a significant predictor of survival in cats with heart failure.
- Further research on body composition is recommended for optimal management strategies.
Background:
Obese people with heart failure have improved survival compared with their normal or underweight counterparts. The purpose of this study was to determine if there is a relationship between body weight or body condition and survival in cats with heart failure.
Hypothesis:
Body weight and body condition score (BCS) are predictors of survival in cats with heart failure.
Animals:
One-hundred and one cats with heart failure (International Small Animal Cardiac Health Council Classes II, IIIa, or IIIb) evaluated between March 2007 and June 2009.
Methods:
Data regarding initial body weight and BCS, subsequent changes in body weight, and treatment were collected from records and compared with survival times.
Results:
Median initial body weight was 5.1 kg (range, 2.2-9.5 kg). Median BCS was 5 (range, 3-9). Of the 68 cats that were discharged from the hospital, median body weight change was 0.0 kg (range, -2.6 to +2.3 kg). Survival time for all 101 cats was 93 days (0-811 days). Survival could be predicted using a model combining initial body weight (P=.02), body weight squared (P=.02), and survival to discharge (P<.001) with a resulting global P value for this model of P<.0001.
Conclusions And Clinical Importance:
Cats with the lowest and highest body weights had reduced survival times compared with those with body weights in the intermediate ranges, suggesting a U-shaped relationship between body weight and survival. Additional research into the effects of body composition could help to determine optimal management of cats with heart failure.
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