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Updated: Jun 9, 2026

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice
Published on: March 15, 2024
Gender, genetic risk, and criminal behavior.
Jamie Vaske1, John Paul Wright, Danielle Boisvert
1Department of Criminology and Criminal Justice, Western Carolina University, Cullowhee, NC 28723, USA. jvaske@email.wcu.edu
The threshold hypothesis suggests females have higher risk thresholds for offending. This study found females have a higher genetic risk threshold but fewer genetic risks than males, challenging the hypothesis.
Area of Science:
- Behavioral genetics
- Criminology
- Developmental psychology
Background:
- The threshold hypothesis posits females offend less due to higher risk thresholds.
- It predicts female offenders have greater genetic and environmental risk concentrations than males.
Purpose of the Study:
- To investigate the role of genetic factors in female offending.
- To test the predictions of the threshold hypothesis regarding genetic risk in female offenders.
Main Methods:
- Utilized data from the National Longitudinal Study of Adolescent Health (Add Health).
- Analyzed genetic risk factors associated with offending behavior in adolescent and young adult samples.
Main Results:
- Confirmed a higher genetic risk threshold for females compared to males.
- Contradicted the threshold hypothesis: female offenders showed lower genetic risk concentrations than male offenders.
Conclusions:
- While females may have higher genetic risk thresholds, this does not translate to greater genetic risk burden among offenders.
- The etiology of female offending may involve different genetic pathways than previously hypothesized.
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