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Related Experiment Video

Updated: Jun 9, 2026

Brain Slice Stimulation Using a Microfluidic Network and Standard Perfusion Chamber
27:58

Brain Slice Stimulation Using a Microfluidic Network and Standard Perfusion Chamber

Published on: October 1, 2007

Micro-scale and microfluidic devices for neurobiology.

Anne M Taylor1, Noo Li Jeon

  • 1Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC 27599, USA. anne.marion.taylor@gmail.com

Current Opinion in Neurobiology
|August 27, 2010
PubMed
Summary

Microfluidic devices offer precise control for cellular neuroscience experiments. These tools enable detailed study of organisms like C. elegans and cultured neurons in controlled environments.

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Area of Science:

  • Neuroscience
  • Biotechnology
  • Cell Biology

Background:

  • Microfluidic devices provide unparalleled spatial and temporal control for biological research.
  • Traditional in vivo studies often lack precise control over experimental parameters.
  • Micro-structures aid in directing cell and organism placement within microfluidic systems.

Purpose of the Study:

  • To review recent advancements in microfluidic devices for cellular neuroscience.
  • To highlight the application of microfluidics in studying whole organisms (e.g., C. elegans) and cultured neurons.
  • To emphasize the benefits of microfluidic control for in vivo-like experimental conditions.

Main Methods:

  • Development of microfluidic devices with integrated micro-structures.

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BioMEMS: Forging New Collaborations Between Biologists and Engineers
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BioMEMS: Forging New Collaborations Between Biologists and Engineers

Published on: November 1, 2007

Preparation of Neuronal Co-cultures with Single Cell Precision
09:06

Preparation of Neuronal Co-cultures with Single Cell Precision

Published on: May 20, 2014

Related Experiment Videos

Last Updated: Jun 9, 2026

Brain Slice Stimulation Using a Microfluidic Network and Standard Perfusion Chamber
27:58

Brain Slice Stimulation Using a Microfluidic Network and Standard Perfusion Chamber

Published on: October 1, 2007

BioMEMS: Forging New Collaborations Between Biologists and Engineers
07:26

BioMEMS: Forging New Collaborations Between Biologists and Engineers

Published on: November 1, 2007

Preparation of Neuronal Co-cultures with Single Cell Precision
09:06

Preparation of Neuronal Co-cultures with Single Cell Precision

Published on: May 20, 2014

  • Precise definition of pharmacological microenvironments.
  • Compatibility with high-resolution microscopy and reproducible assembly.

    • Main Results:

    • Enhanced control over cell and organism placement.
    • Mimicking in vivo conditions with defined and manipulable parameters.
    • Enabling novel investigations in neurobiology through improved experimental access.

    Conclusions:

    • Microfluidic devices are powerful tools for cellular neuroscience research.
    • These devices facilitate detailed studies on model organisms and cultured neurons.
    • Microfluidics opens new avenues for neurobiological discovery by enhancing experimental control and access.