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Related Concept Videos

Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
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Development of the Oral Microbiota01:28

Development of the Oral Microbiota

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Related Experiment Video

Updated: Jun 9, 2026

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
07:26

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology

Published on: August 22, 2022

Dental development in hemifacial microsomia.

E M Ongkosuwito1, P de Gijt, E Wattel

  • 1Department of Orthodontics, Cleft Palate Team and Craniofacial Team, Erasmus MC-Sophia, University Medical Center, Room Sp 1408, Dr Molewaterplein 60, 3015 GJ Rotterdam, the Netherlands. e.ongkosuwito@erasmusmc.nl

Journal of Dental Research
|August 27, 2010
PubMed
Summary
This summary is machine-generated.

This study investigated Hemifacial microsomia (HFM) and found that severe mandibular development issues correlate with delayed dental development in affected individuals. This suggests a link between jaw and tooth formation in HFM patients.

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Published on: November 13, 2013

Area of Science:

  • Craniofacial development
  • Pediatric dentistry
  • Congenital disorders

Background:

  • Hemifacial microsomia (HFM) is a congenital disorder causing facial asymmetry.
  • The relationship between facial asymmetry and asymmetrical dental development in HFM is not well understood.
  • Limited data exist on dental development relative to mandibular development, HFM severity, or changes over time.

Purpose of the Study:

  • To investigate the relationship between mandibular development and dental development in patients with Hemifacial microsomia.
  • To compare dental development between affected and unaffected sides of the face in HFM patients.
  • To analyze dental development patterns in relation to HFM severity and over time.

Main Methods:

  • Dental development scores were compared between affected and unaffected mandibular sides in 84 HFM patients.
  • Data were compared with 451 Dutch control children.
  • Logistic functions modeled dental age over time for Pruzansky/Kaban HFM types.

Main Results:

  • A tendency toward delayed dental development was observed in Pruzansky/Kaban types IIb and III at younger ages.
  • Severe forms of HFM showed temporary delays in tooth formation.
  • The distribution of agenic (missing) teeth was noted.

Conclusions:

  • A significant interaction between mandibular and dental development is suggested in Hemifacial microsomia.
  • Severe mandibular disturbances in HFM appear to impact local dental development.
  • Findings provide insights into the complex interplay of craniofacial structures in congenital disorders.