Clostridium difficile Infections: What Every Clinician Should Know

The leading cause of nosocomial enteric infections in the US is a potentially lethal condition that influences the daily care of medical and surgical patients across all specialties. The incidence is increasing because of the emergence of a new virulent strain, the development of antibiotic resistance, and an increase in infection rates within populations once believed to be at low risk. Current strategies for the prevention, diagnosis, and treatment are cited. Transmission can be minimized with the use of gloves and gowns; proper hand washing with soap and water (alcohol-based washes do not prevent transmission); careful use and proper cleaning of shared patient equipment, such as blood-pressure cuffs, thermometers, and stethoscopes; and the use of bactericidal cleaning solutions. Restricted or judicious antibiotic use will also reduce the incidence of Clostridium difficile infections.