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Related Concept Videos

Proofreading01:43

Proofreading

Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Related Experiment Video

Updated: Jun 9, 2026

Working with Human Tissues for Translational Cancer Research
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Published on: November 26, 2015

Reviewing manuscripts for biomedical journals.

Gus M Garmel1

  • 1Emergency Medicine Physician, Santa Clara Medical Center; Stanford/Kaiser Emergency Medicine Residency Program, Emergency Medicine (Surgery), Stanford University. gus.garmel@kp.org

The Permanente Journal
|August 27, 2010
PubMed
Summary

Writing for scientific publication is challenging. Improving manuscript quality and understanding the peer-review process are key for researchers and readers in the biomedical field.

Area of Science:

  • Biomedical Literature
  • Scientific Communication

Background:

  • Writing for scientific publication presents challenges for professionals, impacting research dissemination.
  • Author emotions and enjoyment during the writing process may influence manuscript outcomes.
  • Existing literature covers manuscript preparation and the review process.

Purpose of the Study:

  • To describe essential elements for improving scientific writing.
  • To discuss the biomedical literature review process, reviewer importance, and responsibilities.
  • To provide insights for interpreting medical literature.

Main Methods:

  • Review of existing literature on scientific writing and peer review.
  • Discussion of manuscript components and the peer-review system.

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  • Analysis of reviewer roles and qualities in scientific publishing.
  • Main Results:

    • Scientific writing requires practice and attention to essential manuscript elements.
    • The peer-review process is crucial for scientific integrity but faces challenges regarding reviewer accountability.
    • Reviewers play a vital role, and their contributions are often underappreciated.

    Conclusions:

    • Improving scientific writing is essential for effective research communication.
    • Understanding and refining the peer-review process enhances scientific validity.
    • Knowledge of manuscript elements and review dynamics benefits authors, reviewers, and readers.