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Updated: Jun 9, 2026
08:07
Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
Published on: April 12, 2019
Osteosarcoma masked by osteomyelitis and cellulitis in a dog
1Ontario Veterinary College, University of Guelph, Department of Clinical Studies, Guelph ON, N1G 2W1, Canada. sboston@uoguelph.ca
Summary
Osteomyelitis can mask osteosarcoma in dogs, presenting a diagnostic challenge. This case highlights the importance of suspecting primary bone tumors even with initial signs of infection.
Area of Science:
- Veterinary Oncology
- Canine Pathology
- Diagnostic Imaging
Background:
- Osteosarcoma is a common primary bone tumor in dogs.
- Infectious osteomyelitis can present with similar clinical signs and radiographic findings.
Observation:
- A German Shepherd presented with cellulitis and osteomyelitis of the forelimb and humerus.
- Initial diagnostics including ultrasound, radiography, cytology, and histopathology were consistent with infection.
- Despite debridement and antibiotics, the condition progressed, revealing a lytic lesion.
Findings:
- A lytic lesion of the proximal humerus was identified.
- Metastatic disease to the lungs was confirmed via CT scan.
- Post-mortem examination confirmed osteosarcoma with widespread metastasis.
Implications:
- This is the first reported case of osteomyelitis masking osteosarcoma in a dog.
- Clinicians should maintain a high index of suspicion for primary bone tumors in cases with ambiguous findings.
- Early and accurate diagnosis is crucial for appropriate canine cancer management.
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