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Updated: Jun 9, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Dry lung syndrome: a distinct clinical entity.
Arvind Sehgal1, Johny Vakayil Francis, Hazel Ang
1Monash Newborn, Monash Medical Centre, Monash University, 246, Clayton Road, Clayton, VIC 3168, Australia. Arvind.Sehgal@southernhealth.org.au
Preterm prolonged rupture of membranes can cause pulmonary issues in infants. Early recognition and tailored ventilatory support, alongside antenatal monitoring, are crucial for improving outcomes in dry lung syndrome.
Area of Science:
- Neonatal Medicine
- Pulmonology
- Obstetrics
Background:
- Preterm prolonged rupture of membranes (PPROM) can lead to immediate pulmonary insufficiency in neonates.
- Dry lung syndrome (DLS) is an under-recognized condition associated with PPROM, characterized by functional lung hypoplasia.
- Existing literature on DLS is sparse, with a need for clearer understanding and management strategies.
Observation:
- This study details two cases of neonates with PPROM and suspected DLS.
- Both cases shared similar antenatal and immediate postnatal courses.
- However, the infants experienced drastically different clinical outcomes.
Findings:
- Functional lung hypoplasia is the proposed etiopathogenesis of DLS.
- Higher ventilatory pressures in the initial 1-2 days may enhance oxygenation in affected infants.
- The study highlights the variability in outcomes despite similar initial presentations.
Implications:
- Antenatal assessment of maternal liquor volume and fetal breathing movements is recommended for high-risk pregnancies.
- In-utero transfer to perinatal centers for delivery is advised.
- Experienced neonatal staff attendance is critical for optimizing management and outcomes in PPROM cases.
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