CNS and PNS effects of nimodipine

Calcium ions play a decisive role in a large number of processes dealing with development, regeneration after damage, and aging of elements of the nervous system. Nimodipine, a member of the 1,4-dihydropyridine chess of calcium-channel blockers, has proved to influence the calcium metabolism of neurons. This review focuses on the results of recent studies on the role of nimodipine in both the central and peripheral nervous system, during or after events that threaten the integrity or function of the nervous system.