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[Studies on Stachys sieboldii MIQ. II. Anti-anoxia action and the active constituents]
J Yamahara1, T Kitani, H Kobayashi
1Kyoto Pharmaceutical University, Japan.
Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan
|December 1, 1990
Abstract:
During screening for the development of drugs from natural products, methanolic extract of tuber of Stachys sieboldii MIQ. (Labiatae) significantly inhibited the lethal induced by KCN in mice. The methanolic extract was fractionated by column chromatography to identify the active constituents. Acteoside and stachysoside C, phenylethanoid glycoside, have a significant effect on the KCN-induced anoxia model.