[Effect of experimental ischemia on the hearing organ of guinea pigs in electron-microscopic studies]

The histologic evaluation of the influence of unilateral stimulation and of the ligation of vertebral artery on the hearing organ in guinea pigs were studied. The material consisted of 20 guinea pigs of both sexes, weight 250-300 g. It was proved that the ligation of the unilateral vertebral artery caused hypoxial lesions in the brainstem and subsequently secondary lesions in the spiral ganglion. One side stimulation of above mentioned artery caused the unilateral brainstem lesions as well as the spiral ganglion ones. The more expressed lesions were found in the cochlear nuclei in the ligation group.