Related Experiment Videos
[Manifestations of pseudo-allergy in different diseases in children]
Insights
This study followed 57 children with pseudoallergic reactions, finding associated pathologies like eczema and urticaria. Treatment with histaglobulin or zaditen led to significant clinical improvements in pediatric patients.
Area of Science:
- Pediatric dermatology
- Clinical immunology
- Allergy research
Context:
- Pseudoallergic reactions in children present with diverse dermatological manifestations.
- These reactions are often linked to underlying pediatric pathologies.
- Understanding these associations is crucial for effective management.
Purpose:
- To investigate the clinical characteristics and associated pathologies of pseudoallergic reactions in children.
- To evaluate the efficacy of histaglobulin and zaditen in treating these conditions.
Summary:
- Fifty-seven children (1-14 years) with pseudoallergic reactions (eczema, urticaria, Quincke's edema) were studied.
- Infants showed hypertensive hydrocephalic syndrome; older children had vegetovascular dystonia or gastrointestinal issues.
- Treatment with histaglobulin or zaditen resulted in notable positive clinical changes.
Impact:
- Highlights the link between pseudoallergic reactions and distinct pediatric health conditions.
- Demonstrates the therapeutic potential of histaglobulin and zaditen in managing pediatric pseudoallergic reactions.
- Informs clinical practice for diagnosing and treating children with allergic-like skin conditions.
Abstract:
Fifty-seven children aged 1 to 14 years with pseudoallergic reactions were followed up. The reactions manifested in the form of eczema, neurodermatitis, urticaria, and Quincke's edema. All the patients showed different pathology associated with the above-indicated skin reactions. The infants presented with the hypertensive hydrocephalic syndrome whereas the elder children with vegetovascular dystonia, biliary and gastrointestinal diseases. The treatment of the revealed pathological process, that included administration of histaglobulin or zaditen, brought about well-defined positive clinical changes.