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Updated: Aug 5, 2026

Protocol for Long Duration Whole Body Hyperthermia in Mice
Published on: August 25, 2012
[Infusion therapy in sessions of general artificial hyperthermia using large doses of insulin in cancer patients]
Abstract:
A scheme of infusion correction of water-electrolyte shifts occurring during general artificial hyperthermia sessions (rectal t degrees-40-42 degrees C) employing large insulin doses (100-1120 U) in cancer patients has been suggested. The infusion therapy according to the technique described was used during 103 general artificial hyperthermia sessions in 58 patients. This made it possible to maintain physiologically normal blood plasma levels of glucose, Na+, K+, calcium, inorganic phosphates, normal acid-base balance, adequate hydration and circulating blood volume.
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