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Organophosphate poisoning.

J A Rivera1, M Rivera

  • 1Department of Medicine, Ramón Ruíz Arnau University Hospital, School of Medicine, Universidad Central del Caribe.

Boletin De La Asociacion Medica De Puerto Rico
|September 1, 1990
PubMed
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Organophosphate insecticide poisoning in adults, often from suicidal ingestion, caused symptoms like nausea and increased bronchial secretions. Fortunately, no deaths or delayed toxicity were observed in this series.

Area of Science:

  • Toxicology
  • Clinical Medicine
  • Epidemiology

Background:

  • Organophosphate compounds are widely used as insecticides.
  • These compounds are frequently implicated in serious human toxicity cases.
  • Understanding poisoning patterns and outcomes is crucial for public health.

Purpose of the Study:

  • To review adult cases of organophosphate poisoning.
  • To identify common exposure routes, symptoms, and signs.
  • To analyze laboratory findings, treatment outcomes, and potential delayed toxicity.

Main Methods:

  • Retrospective review of 14 adult organophosphate poisoning cases.
  • Data collected from January 1986 to January 1990 at HURRA.
  • Analysis of patient demographics, exposure, clinical presentation, laboratory results, treatment, and follow-up.

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Main Results:

  • All 14 cases were male, with ingestion (suicidal attempt) being the most common exposure route (8/14).
  • Nausea (6/14) and increased bronchial secretions (8/14) were the most frequent symptom and sign, respectively.
  • Common laboratory findings included leukocytosis (10/14), hyperglycemia (5/14), and hypokalemia (4/14). No seizures or ventricular arrhythmias occurred. One patient required mechanical ventilation for respiratory failure. No mortality was observed.

Conclusions:

  • Organophosphate poisoning in this cohort presented with specific clinical and laboratory features.
  • Standard treatment protocols were effective, with no mortality or delayed toxicity reported.
  • This study highlights the importance of prompt management and monitoring for severe complications.