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Cell potential and motility of isolated mammalian vestibular sensory cells
H P Zenner1, U Zimmermann, A H Gitter
1HNO Hearing Research Laboratories, University of Tübingen, F.R.G.
Hearing Research
|December 1, 1990
Abstract:
Vestibular hair cells (VHCs) were isolated from the guinea pig inner ear. Using the whole cell variant of the patch clamp recording technique a zero current cell potential of -63.1 +/- 9.9 mV was measured in macular hair cells. Depolarization and repolarization were accompanied by mechanical responses of the solitary VHCs. In addition to the evoked motile events spontaneous shape changes of VHCs were observed. Implications for vestibular micromechanics of the observed evoked force generation in VHCs are discussed.