1Service de Neurologie et de Neuropsychologie, Université Pierre et Marie Curie, Hôpital de la Salpêtrière, Paris.
Oligodendrocytes, the central nervous system's myelin-forming cells, originate from bipotential O-2A precursor cells. Extracellular factors, often from type 1 astrocytes, guide their differentiation into oligodendrocytes or type 2 astrocytes.
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