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Long-term weight changes in treated hyperthyroid and hypothyroid patients.

J Pears1, R T Jung, A Gunn

  • 1Department of Medicine, Ninewells Hospital and Medical School, Dundee.

Scottish Medical Journal
|December 1, 1990
PubMed
Summary
This summary is machine-generated.

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Patients treated for thyrotoxicosis experienced significant weight gain regardless of treatment. Those treated for hypothyroidism did not lose weight, indicating a need for dietary advice during thyroid dysfunction management.

Area of Science:

  • Endocrinology
  • Metabolic Disorders
  • Thyroid Disease

Background:

  • Thyrotoxicosis is a condition of excess thyroid hormones, often leading to weight loss.
  • Treatment modalities for thyrotoxicosis include carbimazole, thyroidectomy, and radioiodine therapy.
  • The impact of these treatments on subsequent body weight requires further investigation.

Purpose of the Study:

  • To compare the effects of three distinct treatments for thyrotoxicosis on patient body weight.
  • To examine the influence of thyroxine replacement therapy on body weight in hypothyroid patients.

Main Methods:

  • A retrospective survey was conducted on 65 patients diagnosed with thyrotoxicosis.
  • Body weight changes were analyzed one year after initiating treatment for thyrotoxicosis.

Related Experiment Videos

  • Body weight changes were also analyzed in 25 patients receiving thyroxine for hypothyroidism.

    • Main Results:

    • All three treatment groups for thyrotoxicosis (carbimazole, thyroidectomy, radioiodine) showed significant mean weight gain (5.4kg, 6.3kg, 7.4kg respectively) within one year.
    • No significant difference in weight gain was observed between the three treatment groups for thyrotoxicosis.
    • Patients treated for hypothyroidism experienced minimal weight change (-0.6kg) after 12 months of therapy.

    Conclusions:

    • Treatment for thyrotoxicosis consistently leads to body weight gain, irrespective of the therapeutic approach.
    • Patients with primary hypothyroidism do not exhibit significant weight loss following thyroxine replacement therapy.
    • Dietary counseling should be considered at the initiation of thyroid dysfunction treatment to manage expected weight changes.