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[Brucellosis in a 3 month-old infant]
E Varon1, R Cohen, C A Bouhanna
1Services de Microbiologie et de Néonatologie, Hôpital Intercommunal de Créteil.
Archives Francaises De Pediatrie
|October 1, 1990
Summary
Brucellosis in infants is challenging to diagnose. This case highlights rare human-to-human transmission from mother to child, successfully treated with ceftriaxone and rifampin.
Area of Science:
- Pediatric Infectious Diseases
- Bacterial Pathogenesis
- Neonatal Immunology
Context:
- Brucellosis is a zoonotic disease with nonspecific symptoms in infants, making diagnosis difficult.
- Infantile brucellosis can be mild and self-limiting, complicating early detection and treatment.
- This case involves a 3-month-old infant diagnosed with Brucella melitensis during bronchiolitis.
Purpose:
- To report a rare case of human-to-human Brucella melitensis transmission from mother to infant.
- To discuss the diagnostic challenges of infantile brucellosis.
- To evaluate a treatment regimen for pediatric brucellosis.
Summary:
- A 3-month-old infant with bronchiolitis presented with Brucella melitensis bacteremia.
- Maternal serum revealed high Brucella agglutinin titers, suggesting mother-to-child transmission via breastfeeding.
- The infant was successfully treated with ceftriaxone and rifampin, avoiding potential complications from other antibiotics.
Impact:
- This case underscores the importance of considering brucellosis in infants, even with nonspecific symptoms.
- It highlights a rare route of transmission (mother-to-child) and informs diagnostic approaches.
- Successful treatment with ceftriaxone and rifampin provides a viable therapeutic option for pediatric brucellosis.