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Updated: Jun 9, 2026

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
Published on: August 11, 2012
Chlamydia trachomatis and cervical intraepithelial neoplasia in married women in a Middle Eastern community
M Valadan1, F Yarandi, Z Eftekhar
1Department of Obstetrics and Gynaecology, Mirza Koochak Khan Hospital, Islamic Republic of Iran. mehrnaz_valadan@yahoo.com
Abstract:
The objective of this study was to determine the association between vaginal Chlamydia infection and cervical intraepithelial neoplasia (CIN). Data were collected in a case-control study for 60 patients with CIN in biopsy and 85 control subjects with normal colposcopy and biopsy. Serum antibodies to C trachomatis were associated with an increased risk for CIN [odds ratio (OR) = 7.3; 95% confidence interval (CI) 1.5-35.2)]. There was also a significant association between presence of inclusion bodies for C. trachomatis and CIN (OR = 5.5; 95% CI 2.4-12.4). These results indicate a strong association between CIN and chlamydial cervicitis.
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