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Updated: Jun 9, 2026
08:49
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Outcome after restorative proctocolectomy in children and adolescents
A P Saklani1, N Marsden, M Davies
1Colorectal Department, Singleton Hospital, Sketty Lane, Swansea, UK. asaklani@hotmail.com
Summary
Restorative proctocolectomy (RPC) in pediatric patients with ulcerative colitis, familial adenomatous polyposis, and idiopathic megarectum yields good functional outcomes and acceptable quality of life (QOL). This surgical approach offers promising results for young individuals requiring complex gastrointestinal reconstruction.
Area of Science:
- Pediatric surgery
- Gastroenterology
- Colorectal surgery
Background:
- Ulcerative colitis (UC), familial adenomatous polyposis (FAP), and idiopathic megarectum are conditions requiring surgical intervention in children and adolescents.
- Restorative proctocolectomy (RPC) is a complex procedure with functional and quality of life (QOL) implications.
Purpose of the Study:
- To evaluate the functional outcomes and QOL following RPC in pediatric patients.
- To assess the safety and efficacy of RPC in managing UC, FAP, and idiopathic megarectum in a young population.
Main Methods:
- A cohort of 21 pediatric patients (median age 15 years) underwent RPC between 1995 and 2006.
- Data collected included indication, use of covering ileostomy, morbidity, mortality, and long-term functional outcomes via questionnaire.
- Faecal incontinence was assessed using the Cleveland Clinic Scoring (CCS) System, and QOL using the modified McMaster proforma.
Main Results:
- No mortality was observed. At a median follow-up of 65.5 months, all pouches were intact, with one patient requiring a long-standing ileostomy.
- Median daytime and nocturnal stool frequencies were 4 and 0, respectively. The mean CCS was 1.47.
- Eighteen of 20 patients reported satisfaction with the outcome; however, two experienced worse QOL, one developed a permanent stoma post-pouch sepsis, and another had pouchitis.
Conclusions:
- Restorative proctocolectomy (RPC) is a viable surgical option for children and adolescents with UC, FAP, and idiopathic megarectum.
- The procedure demonstrates good functional outcomes and acceptable quality of life (QOL) in this pediatric cohort.
- RPC offers a favorable risk-benefit profile for young patients requiring complex colorectal reconstruction.
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