Pediatric psychotropic medication initiation and adherence: a literature review based on social exchange theory

Vanya Hamrin1, Erin M McCarthy, Veda Tyson

  • 1Yale University School of Nursing, Yale Univsersity, New Haven, Connecticut, USA. Vanya.Hamrin@yale.edu

Insights

Family decisions on pediatric psychotropic medication involve weighing benefits like symptom improvement against costs such as side effects and stigma. Adherence is influenced by diagnosis acceptance, education, and provider relationships.

Area of Science:

  • Child and Adolescent Psychiatry
  • Behavioral Health
  • Pharmacology

Background:

  • Psychotropic medication initiation and adherence in children and adolescents is a significant clinical challenge.
  • Understanding family decision-making processes is crucial for effective treatment.
  • Social exchange theory provides a framework for analyzing these decisions.

Purpose of the Study:

  • To explore factors influencing families' decisions regarding psychotropic medication initiation, adherence, and discontinuation in pediatric populations.
  • To examine the costs and benefits associated with psychotropic medication adherence from a family perspective.
  • To evaluate the impact of family demographics and provider relationships on adherence.

Main Methods:

  • A literature review of international and U.S. studies.
  • Databases searched include Medline, CINAHL, and PsycInfo.
  • Social exchange theory was used as a theoretical framework.

Main Results:

  • Medication benefits include symptom improvement, better school performance, and reduced parenting stress.
  • Costs involve adverse effects, stigma, lack of efficacy, and concerns about personality changes.
  • Diagnosis acceptance and provider trust positively impact adherence, while psychosocial alternatives are often preferred.

Conclusions:

  • Family attitudes, beliefs, and perceptions significantly shape medication treatment decisions.
  • Medication psychoeducation has variable effects on adherence.
  • Adolescents gain more influence over adherence decisions as they mature.
Abstract

Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Social Exchange Theory02:06

Social Exchange Theory

We have discussed why we form relationships, what attracts us to others, and different types of love. But what determines whether we are satisfied with and stay in a relationship? One theory that provides an explanation is social exchange theory. According to social exchange theory, we act as naïve economists in keeping a tally of the ratio of costs and benefits of forming and maintaining a relationship with others (Rusbult & Van Lange, 2003).
Social Exchange Theory01:26

Social Exchange Theory

As formulated by John Thibaut and Harold Kelley, Social Exchange Theory explains human relationships as economic-like exchanges that maximize rewards and minimize costs. This theory suggests that individuals engage in relationships to gain benefits and reduce burdens, similar to economic transactions. It has been widely applied to various types of relationships, including romantic, professional, and social interactions.Rewards and Costs in RelationshipsRelationship rewards include emotional...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...