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Related Concept Videos

The Periodic Table03:25

The Periodic Table

As early chemists discovered more elements, they realized that various elements could be grouped by their similar chemical behaviors. One such grouping includes lithium (Li), sodium (Na), and potassium (K). All of these elements are shiny, conduct heat and electricity well, and have similar chemical properties. A second grouping includes calcium (Ca), strontium (Sr), and barium (Ba), which also are shiny, good conductors of heat and electricity, and have chemical properties in common. However,...
The Periodic Table And Organismal Elements01:27

The Periodic Table And Organismal Elements

Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally occurring, and only a few of them are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.
Periodic Table Provides Information...
The Periodic Table and Organismal Elements00:57

The Periodic Table and Organismal Elements

Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally-occurring, and fewer still are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.The Periodic Table Provides Information about...
The Periodic Table and Organismal Elements01:27

The Periodic Table and Organismal Elements

Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally occurring, and only a few of them are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.
Periodic Table Provides Information...
The Periodic Table and Organismal Elements00:57

The Periodic Table and Organismal Elements

Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally-occurring, and fewer still are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.The Periodic Table Provides Information about...
Periodic Classification of the Elements04:00

Periodic Classification of the Elements

The periodic table arranges atoms based on increasing atomic number so that elements with the same chemical properties recur periodically. When their electron configurations are added to the table, a periodic recurrence of similar electron configurations in the outer shells of these elements is observed. Because they are in the outer shells of an atom, valence electrons play the most important role in chemical reactions. The outer electrons have the highest energy of the electrons in an atom...

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Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods
05:34

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods

Published on: June 6, 2025

Expanding the biological periodic table.

Javier Seravalli1, Stephen W Ragsdale

  • 1Department of Biochemistry, University of Nebraska-Lincoln, 1901 Vine Street, Lincoln, NE 68588, USA.

Chemistry & Biology
|August 28, 2010
PubMed
Summary

Researchers developed a new method to identify metalloproteins across entire genomes. This approach helps explore the largely unknown metalloproteome, crucial for understanding biological functions.

Area of Science:

  • Biochemistry
  • Proteomics
  • Bioinorganic Chemistry

Background:

  • Metal ions are essential for protein function and structure in biological systems.
  • The complete set of metal-binding proteins (metalloproteome) remains largely uncharacterized.
  • Understanding metalloproteins is key to deciphering numerous biological processes.

Purpose of the Study:

  • To present a novel genome-wide strategy for identifying metalloproteins.
  • To facilitate a more comprehensive exploration of the metalloproteome.
  • To advance the understanding of metal ion roles in biological systems.

Main Methods:

  • Development of a high-throughput approach for metalloprotein identification.
  • Application of the method on a genome-wide scale.

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Universal Molecular Retention with 11-Fold Expansion Microscopy

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  • Bioinformatic analysis to identify potential metalloproteins.
  • Main Results:

    • A new strategy for identifying metalloproteins was successfully developed.
    • The approach enables genome-wide metalloprotein discovery.
    • This work lays the foundation for further metalloproteome research.

    Conclusions:

    • The described approach significantly advances the ability to study metalloproteins.
    • Genome-wide identification of metalloproteins is now more feasible.
    • Further research can build upon this method to uncover the full scope of the metalloproteome.