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Functional association of interleukin-18 gene -607 C/A promoter polymorphisms with endometriosis
Lokman Ayaz1, Sevim Karakaş Çelik, Filiz Çayan
1Department of Biochemistry, School of Medicine, Mersin University, Mersin, Turkey.
Fertility and Sterility
|August 28, 2010
Abstract:
This study evaluated for the first time the relationship between interleukin-18 (IL-18) C607A genotypes and endometriosis in 135 women with endometriosis and 84 controls. In the study population, IL-18 -607∗A homozygote and A allele were positively correlated with the risk of developing endometriosis or the stage of endometriosis.
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