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Published on: August 9, 2024
Validation of upper extremity post-thrombotic syndrome outcome measurement in children
Neil A Goldenberg1, Elizabeth Pounder, R Knapp-Clevenger
1Department of Pediatrics, Section of Hematology/Oncology/Bone Marrow Transplantation and the Mountain States Hemophilia and Thrombosis Center, University of Colorado Denver and The Children's Hospital, Aurora, CO, USA. neil.goldenberg@ucdenver.edu
Abstract:
Using the Manco-Johnson instrument in a derivation cohort of 107 children with or without a central venous catheter, upper extremity physical findings of post-thrombotic syndrome were absent, and the pain score was 0 in all but one child. Interrater reliability in an independent validation cohort (n = 38) of children with or without upper extremity deep venous thrombosis was 97%-100%.

