Ionic liquid under ultrasonic irradiation towards a facile synthesis of pyrazolone derivatives
Hongjun Zang1, Qiuhong Su, Yingming Mo
1Department of Environmental and Chemistry Engineering, Tianjin Polytechnic University, State Key Laboratory of Hollow Fiber Membrane Materials and Processes, Tianjin 300160, China. zanghongjun@tjpu.edu.cn
Ultrasonics Sonochemistry
|August 28, 2010
Abstract:
Ionic liquid [HMIM]HSO(4) was found to be an efficient catalyst for the synthesis of 4-[(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-phenyl-methyl]-5-methyl-2-phen-yl-1,2-dihydro-pyrazol-3-ones through the condensation reaction of arylaldehydes and 3-methyl-1-phenyl-5-pyrazolone under ultrasonic irradiation at room temperature. The present methodology offers several advantages such as excellent yields, simple procedure and mild conditions.
