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[Changes in upper gastrointestinal motility during scleroderma].

G Bassotti1, C Betti, M A Pelli

  • 1Laboratorio di Motilità Intestinale, Cattedra di Gastroenterologia, Istituto di Gastroenterologia e Endoscopia Digestiva, Università di Perugia.

Medicina (Florence, Italy)
|July 1, 1990
PubMed
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Scleroderma, a systemic collagen disease, often affects the upper gut, causing esophageal motility issues and potential small bowel complications. Manometric techniques aid in understanding these gastrointestinal dysfunctions in scleroderma patients.

Area of Science:

  • Gastroenterology
  • Rheumatology
  • Systemic Autoimmune Diseases

Context:

  • Scleroderma (progressive systemic sclerosis) frequently impacts the upper gastrointestinal tract.
  • Esophageal motility alterations are common, leading to severe, refractory esophagitis.
  • Small bowel involvement occurs, particularly in advanced stages, presenting diverse complications.

Purpose:

  • To investigate the gastrointestinal motility alterations in scleroderma.
  • To highlight the clinical significance of upper gut involvement in scleroderma.
  • To explore the utility of manometric techniques in understanding scleroderma-associated GI dysfunction.

Summary:

  • Scleroderma commonly causes esophageal motility disorders and esophagitis.
  • Small bowel complications like malabsorption and pseudo-obstruction are observed.

Related Experiment Videos

  • Manometry can detect and help elucidate altered gastrointestinal motility in scleroderma and other collagenopathies.

    • Impact:

    • Improved understanding of scleroderma's gastrointestinal pathophysiology.
    • Potential for earlier diagnosis and management of GI complications.
    • Manometry as a valuable tool for research and clinical practice in collagen vascular diseases.