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Updated: Jun 9, 2026

Ultrasound-based Pulse Wave Velocity Evaluation in Mice
Published on: February 14, 2017
Optimization of Doppler echocardiographic velocity measurements using an automatic contour detection method
Emmanuel Gaillard1, Lyes Kadem, Marie-Annick Clavel
1Institut de Recherches Cliniques de Montreal, University of Montreal, Montreal, Quebec, Canada. emmanuel.gaillard@ircm.qc.ca
An automated method using active contour models significantly reduces variability in Doppler echocardiographic velocity measurements (DEVM). This tool enhances diagnostic accuracy for heart valve conditions and speeds up analysis.
Area of Science:
- Cardiovascular Imaging
- Medical Image Analysis
- Echocardiography
Background:
- Doppler echocardiographic velocity measurements (DEVM) exhibit significant intra- and interobserver variability.
- Variability in DEVM can lead to diagnostic errors in assessing heart valve dysfunction severity.
Purpose of the Study:
- To develop and validate an automatic method for Doppler velocity wave contour detection using active contour models.
- To reduce variability and increase the speed of DEVM.
Main Methods:
- An automatic Doppler velocity wave contour detection method based on active contour models was developed.
- The method was validated by comparing its results with manual measurements from two experienced echocardiographers.
- Measurements included maximum velocity (Vmax), mean velocity (Vmean), and velocity-time integral (VTI) in 30 patients with aortic/mitral stenosis and 20 with normal sinus rhythm.
Main Results:
- The automatic method showed very good agreement with manual measurements.
- Bias values were small: -3.9% to 0.5% for Vmax, -4.6% to -1.4% for Vmean, and -3.6% to 4.4% for VTI.
- The computation time for the automatic method was approximately 5 seconds.
Conclusions:
- The developed automatic method is a valuable tool for eliminating intra- and interobserver variability in DEVM.
- This can improve diagnostic accuracy for cardiovascular diseases, particularly heart valve dysfunctions.
- The method offers faster measurements and is easily implementable in standard echocardiographic systems.
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