[The functional status of the peripheral blood neutrophilic granulocytes determined by the corona-forming index during tumor growth]

It was established that the formation of a primary neoplastic focus, a recurrence of the disease, and the development of a second focus in a previously treated oncological patient occur mainly in reduced indices of corona formation; in extension of a malignant process (carcinoma of the stomach and lungs), in contrast, the corona-forming activity of the segmented neutrophils is characteristically increased. The studied test may be of prognostic importance in appraising the efficacy of the treatment of patients with carcinoma of this localization. The mechanisms determining the trend of changes in the corona formation in a neoplastic process require further study.