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Related Experiment Video

Updated: Jun 9, 2026

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge

Published on: January 20, 2023

Jugular venous hemodynamic changes with aging.

Chih-Ping Chung¹, Ya-Ju Lin, A-Ching Chao

¹Department of Neurology, Taipei Veterans General Hospital, National Yang Ming University, Taipei, Taiwan.

Ultrasound in Medicine & Biology

|August 31, 2010

Summary

This summary is machine-generated.

Aging impacts cerebral venous outflow. This study establishes normal internal jugular vein (IJV) hemodynamic parameters in a large population, revealing age-related changes like reduced flow velocity and increased jugular venous reflux (JVR).

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Area of Science:

Neurology
Vascular Biology
Medical Imaging

Background:

Cerebral venous outflow insufficiency, particularly via the internal jugular vein (IJV), is linked to neurological disorders.
A lack of comprehensive normal reference data for IJV hemodynamics across diverse age groups has hindered clinical and research applications.

Purpose of the Study:

To establish a normal reference set of internal jugular vein (IJV) hemodynamic parameters in a large, healthy population.
To investigate age-related changes in IJV hemodynamics and prevalence of jugular venous reflux (JVR).

Main Methods:

Color-coded duplex sonography was utilized to assess the IJVs of 349 healthy subjects (aged 16-89 years).
Hemodynamic parameters including lumen area, mean velocity, and flow volume were analyzed.
The frequency of left jugular venous reflux (JVR) was recorded.

Main Results:

Increasing age correlated with increased IJV lumen area and decreased time-averaged mean velocity in both IJVs.
A decreased proportion of total venous drainage was observed in the left IJV with aging.
The prevalence of left jugular venous reflux (JVR) increased significantly with age.

Conclusions:

This study provides essential normative IJV hemodynamic data for clinical and research use.
Aging is associated with increased left IJV outflow impedance, characterized by reduced drainage proportion, higher JVR, dilated lumen, and slower flow velocity.