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Updated: Jun 9, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
Published on: May 17, 2024
Paraspinal malignant ossifying fibromyxoid tumor with spinal involvement
Jaypal Reddy Sangala1, Paul Park, Mila Blaivas
1Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan 48109-5338, USA.
Abstract:
Ossifying fibromyxoid tumors (OFT), first described in 1989 by Enzinger et al., are rare lesions; malignant OFT (MOFT) are even rarer. We report a large recurrent paraspinal MOFT invading the spine and causing epidural compression in a 70-year-old male, despite prior debulking and radiotherapy. Paraspinal involvement of these tumors has been reported only twice before. We describe its imaging, pathology, and also review the pertinent literature.

