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Ipsilateral transversus abdominis plane block provides effective analgesia after appendectomy in children: a
John Carney1, Olivia Finnerty, Jassim Rauf
1Department of Anaesthesia, Clinical Sciences Institute, National University of Ireland, Galway, Ireland. john.laffey@nuigalway.ie
Insights
The transversus abdominis plane (TAP) block significantly reduced pain and morphine use in children after appendectomy. This study confirms its effectiveness as part of multimodal analgesia, with no observed complications.
Area of Science:
- Pediatric Anesthesiology
- Regional Anesthesia
- Pain Management
Background:
- Transversus abdominis plane (TAP) block is effective for postoperative pain in adults.
- Efficacy in pediatric patients undergoing abdominal surgery is not well-established.
- Lack of randomized clinical trials in children necessitates further investigation.
Purpose of the Study:
- To evaluate the analgesic efficacy of unilateral TAP block in children.
- To assess pain management over the first 48 postoperative hours after appendectomy.
- To compare TAP block with ropivacaine versus placebo in a pediatric appendectomy cohort.
Main Methods:
- Randomized, controlled, double-blind clinical trial involving 40 children.
- Unilateral TAP block with ropivacaine or placebo administered post-anesthesia induction.
- Standard postoperative analgesia included IV morphine, diclofenac, and acetaminophen.
Main Results:
- TAP block significantly reduced mean morphine requirements (10.3 vs 22.3 mg) in the first 48 hours (P < 0.01).
- Reduced visual analog scale pain scores at rest and during movement were observed.
- No significant differences in sedation, nausea, vomiting, or TAP block-related complications.
Conclusions:
- Unilateral TAP block is a safe and effective component of multimodal analgesia for pediatric appendectomy.
- Provides superior postoperative analgesia compared to placebo in the first 48 hours.
- Supports the use of TAP block for pain management in children undergoing abdominal surgery.
Background:
The transversus abdominis plane (TAP) block provides effective postoperative analgesia in adults undergoing major abdominal surgery. Its efficacy in children remains unclear, with no randomized clinical trials in this population. In this study, we evaluated its analgesic efficacy over the first 48 postoperative hours after appendectomy performed through an open abdominal incision, in a randomized, controlled, double-blind clinical trial.
Methods:
Forty children undergoing appendectomy were randomized to undergo unilateral TAP block with ropivacaine (n = 19) versus placebo (n = 21) in addition to standard postoperative analgesia comprising IV morphine analgesia and regular diclofenac and acetaminophen. All patients received a standard general anesthetic, and after induction of anesthesia, a TAP block was performed using the landmark technique with 2.5 mg · kg(-1) ropivacaine 0.75% or an equal volume (0.3 mL · kg(-1)) of saline on the ipsilateral side to the incision.
Results:
The TAP block with ropivacaine reduced mean (± SD) morphine requirements in the first 48 postoperative hours (10.3 ± 12.7 vs 22.3 ± 14.7 mg; P < 0.01) compared with placebo block. The TAP block also reduced postoperative visual analog scale pain scores at rest and on movement compared with placebo. Interval morphine consumption was reduced over the first 24 postoperative hours. There were no between-group differences in the incidence of sedation or nausea and vomiting. There were no complications attributable to the TAP block.
Conclusions:
Unilateral TAP block, as a component of a multimodal analgesic regimen, provided superior analgesia compared with placebo in the first 48 postoperative hours after appendectomy in children.
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