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Updated: Jun 9, 2026

A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation
Published on: April 27, 2019
Perioperative variables of ventilatory function and physical capacity in heart transplant patients
Christian Correa Coronel1, Solange Bordignon, André Dias Bueno
1Fisioterapia Cardiologia Pós-Graduação em Fisioterapia Cardiorrespiratória, IC, FUC, Porto Alegre, RS, Brazil.
Introduction:
Heart transplantation is currently the only widely accepted surgical alternative to treat patients with severe heart failure (HF) drug therapy cannot maintain optimal quality of life appropriate.
Objective:
To describe and to compare the values between pre-and postoperative physical capacity and pulmonary patients who underwent heart transplantation.
Methods:
A retrospective cohort composed of patients undergoing heart transplantation between January 2001 to March 2005 in IC-FUC/RS.
Results:
Were included in the 21 individuals. We observed decreased levels of volume and lung capacity (FEV1 and FVC) in the first days after surgery compared to preoperatively (P <0.001) and recovery of these values in the 14th postoperative day (P <0.001). The values of muscle strength showed similar trends in reducing post-operative period compared to preoperative (P <0.001) and recovered on the 14th postoperative day (P <0.001). A useful functional capacity, measured by testing 6-minute walk test (T6') showed improvement in the 14th postoperative day in relation to pre-operatively (P <0.001).
Conclusion:
Changes in ventilatory function of subjects undergoing cardiac transplantation are predictable, but these recover respiratory muscle strength and lung capacity within two weeks, and improve functional capacity useful in relation to pre-operative, the transplantation, when indicated, associated with good functional rehabilitation is very god treatment strategy.
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