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[Catatonic dilemma in a schizoaffective patient with combined lithium-risperidone administration]
Rainer Krähenmann1, Bernhard Küchenhoff, Heinz Böker
1Psychiatrische Universitätsklinik Zürich, Klinik für Affektive Erkrankungen und Allgemeinpsychiatrie ZH Ost, Lenggstrasse 31, Postfach 1931, 8032 Zürich, Schweiz. Rainer.Kraehenmann@puk.zh.ch
Objective:
The case of a schizoaffective patient suffering from a malignant catatonic syndrome following combined lithium-risperidone therapy is explored.
Method:
A case report and relevant deliberations regarding pathophysiology of the catatonic dilemma are discussed.
Conclusions:
There are two critical transitions in the development of a malignant catatonic syndrome. Dopaminergic system and psychopharmacological factors are supposed to play a key role. However, other neurotransmitter systems and the individual predisposition must be considered.
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