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Related Experiment Video

Updated: Jun 9, 2026

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions

Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions

Published on: April 28, 2026

Prospective comparison between double-balloon enteroscopy and spiral enteroscopy.

T Frieling¹, J Heise, W Sassenrath

¹Department of Gastroenterology, Hepatology, Infectiology, Neurogastroenterology, Hematology and Oncology, HELIOS-Clinic Krefeld, Krefeld, Germany. thomas.frieling@helios-kliniken.de

|August 31, 2010

Summary

Double-balloon enteroscopy (DBE) may offer a higher diagnostic yield for small-bowel imaging compared to spiral enteroscopy. Further research is needed to confirm these findings in larger patient cohorts.

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Area of Science:

Gastrointestinal Endoscopy
Small Bowel Imaging
Diagnostic Enteroscopy

Background:

Balloon-guided enteroscopy techniques, including double-balloon enteroscopy (DBE), are established for small-bowel procedures.
No prior prospective studies have directly compared DBE with spiral enteroscopy.

Purpose of the Study:

To prospectively compare the performance of double-balloon enteroscopy (DBE) and spiral enteroscopy in patients undergoing diagnostic enteroscopy.

Main Methods:

A prospective study involving 35 patients assigned to either spiral enteroscopy (n=18) or DBE (n=17).
Comparison of investigation performance metrics including insertion time, depth, duration, and sedoanalgesia requirements.

Main Results:

No significant differences were observed in insertion time, depth, duration, or sedoanalgesia between spiral enteroscopy and DBE.
Abnormalities such as inflammatory changes, ulcers, and angiodysplasia were detected in 40% of investigations.
While pathological findings were similar, the clinical diagnostic yield appeared higher for DBE (47.1%) than spiral enteroscopy (33.4%).

Conclusions:

This study suggests a potentially higher clinical diagnostic yield for double-balloon enteroscopy (DBE) compared to spiral enteroscopy.
Larger prospective studies are required to validate this preliminary finding and confirm the superiority of DBE.