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Removal of viruscide agents by using styrenic resins
I Bartolozzi1, R Solaro, G Mari
1Department of Chemistry and Industrial Chemistry, University of Pisa - Italy.
Journal of Applied Biomaterials & Biomechanics : JABB
|August 31, 2010
Summary
Anionic ion exchange resins effectively remove iodine and iodide from solutions. Surface modification improved viruscide adsorption, with modified mesoporous resins showing high efficiency and stability for disinfection applications.
Area of Science:
- Polymer chemistry
- Materials science
- Biomedical engineering
Background:
- Anionic polystyrene/divinylbenzene ion exchange resins were explored for blood disinfection.
- Resin-iodine complexes showed limited iodine release in physiological solutions.
- Hydrophobicity of resins hinders wettability in biological fluids.
Purpose of the Study:
- To investigate ion exchange resins as iodophores and iodine/iodide removal agents.
- To enhance viruscide adsorption by modifying resin hydrophilicity.
- To assess the stability of modified resins for disinfection.
Main Methods:
- Preparation of resin-iodine complexes.
- Surface modification of Merrifield and Lewatit resins using various hydrophilic reagents.
- Evaluation of iodine/iodide ion removal efficiency.
- Assessment of viruscide adsorption capacity and wettability.
- Testing thermal stability at 180°C.
Main Results:
- All tested ion exchange resins effectively removed iodine and iodide ions from aqueous solutions.
- Surface modification of Merrifield resins increased wettability but reduced viruscide uptake.
- Modified mesoporous Lewatit resins demonstrated rapid and quantitative viruscide removal.
- High hydrophilicity was achieved in some modified Lewatit samples.
- Modified resins retained their properties after heat treatment simulating pyrogen elimination.
Conclusions:
- Cross-linked styrene/divinylbenzene resins are effective viruscide adsorbents.
- Surface modification is crucial for improving resin performance in physiological environments.
- Modified mesoporous resins offer a promising strategy for disinfection applications due to their adsorption capacity and stability.
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