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Updated: Jun 9, 2026

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
Published on: November 5, 2019
Correlation between tissue oxygenation and erythrocytes elasticity
Yu-Tsung Wu1, Arthur Chiou, Chia-Wei Sun
1Institute of Biophotonics and Biophotonics Interdisciplinary Research Center, National Yang-Ming University, Taipei, Taiwan, R.O.C.
Abstract:
In this paper, near-infrared spectroscopy (NIRS) and jumping optical tweezers were used to measure the tissue oxygenation and the elasticity of erythrocytes, respectively. The correlation between tissue oxygenation induced by arterial occlusion test (AOT) and the mechanical properties of individual erythrocytes from a blood sample obtained after AOT was studied. The experimental results show a linear correlation between the oxygenation signal caused by AOT and the elasticity of erythrocytes.
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