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Anesthetic management of a patient with hypertrophic obstructive cardiomyopathy undergoing modified radical
Aliya Ahmed1, Raza A Zaidi, Muhammad Q Hoda
1Department of Anesthesia, Aga Khan University, P.O. Box 3500, Stadium Road, Karachi 74800, Pakistan. aliya.ahmed@aku.edu
Insights
This case study details the successful anesthetic management of a patient with hypertrophic obstructive cardiomyopathy (HOCM) undergoing surgery. Careful hemodynamic control and management of an implantable cardioverter defibrillator (ICD) ensured a positive outcome.
Area of Science:
- Cardiology
- Anesthesiology
Background:
- Hypertrophic obstructive cardiomyopathy (HOCM) is a genetic disorder causing left ventricular outflow tract (LVOT) obstruction.
- Patients may present with diverse symptoms, from asymptomatic to sudden cardiac death.
- Anesthetic management poses challenges due to potential hemodynamic instability.
Observation:
- A 60-year-old patient with a 17-year history of severe HOCM, mitral regurgitation, and prior ventricular tachycardia requiring an implantable cardioverter defibrillator (ICD) and permanent pacemaker (PPM) was scheduled for mastectomy.
- The patient had an ICD requiring deactivation during surgery with external defibrillation preparedness.
- Key anesthetic considerations included avoiding tachycardia, hypovolemia, vasodilation, and increased cardiac contractility to prevent LVOT obstruction exacerbation.
Findings:
- Successful anesthetic management was achieved, maintaining stable hemodynamics throughout the surgical procedure.
- The patient's ICD was safely managed, with external defibrillation readily available.
- The patient was discharged on the seventh postoperative day, indicating a favorable recovery.
Implications:
- This case highlights the importance of meticulous anesthetic planning and execution in patients with HOCM undergoing non-cardiac surgery.
- Effective management strategies can mitigate risks associated with LVOT obstruction and implanted cardiac devices.
- Successful outcomes are achievable with a multidisciplinary approach and vigilant monitoring.
Abstract:
Hypertrophic obstructive cardiomyopathy (HOCM) is a rare genetic disorder characterized by left ventricular outflow tract (LVOT) obstruction. Clinical presentation ranges from absence of symptoms to sudden death. Our 60 year old patient scheduled for left modified radical mastectomy had HOCM since seventeen years with severe LVOT obstruction and mitral regurgitation. An implantable cardioverter defibrillator (ICD) and permanent pacemaker (PPM) was inserted 15 months earlier for ventricular tachycardia. Anesthetic management of these patients presents considerable challenges and requires maintenance of desired hemodynamic parameters and management of specific complications. Factors like tachycardia, hypovolemia, vasodilation and increased cardiac contractility leads to exacerbation of the obstruction. In our patient there was the additional consideration of the ICD which required to be turned off during surgery with full provision for external defibrillation. We managed to successfully maintain the desired hemodynamics throughout the surgery and the patient was discharged home on the seventh postoperative day.
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