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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Problem aspects of diagnostics and surgical treatment of Itsenko-Cushing syndrome]
Abstract:
The author has analyzed results of examination and treatment of 142 patients with Itsenko-Cushing syndrome. It was established that careful observation of the diagnostic algorithm (estimation of the blood cortisol, adrenocorticotropic hormone level, tests with 8 mg dexamethasone, MRI of adrenal glands and hypophysis with obligatory using contrast paramagnetic substances) allowed differentiation of basic forms of endogenous hypercorticalism: Itsenko-Cushing disease in 83.1%, cortisol-productive adenoma cases in 16.9%. This approach ensures rational strategy of treatment, good outcomes and high quality of life.
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