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Determinants of eczema: population-based cross-sectional study in Germany
C J Apfelbacher1, T L Diepgen, J Schmitt
1Department of Clinical Social Medicine, University Hospital Heidelberg, Thibautstrasse 3, Heidelberg, Germany. christian.apfelbacher@med.uni-heidelberg.de
Allergy
|September 1, 2010
Summary
Family history of allergies is the strongest eczema determinant in children. Perinatal health issues like infections and jaundice after birth also increase eczema risk, highlighting early life factors.
Area of Science:
- Pediatric Dermatology
- Epidemiology
- Environmental Health
Background:
- Eczema is a prevalent chronic inflammatory skin condition in children and adolescents.
- Understanding eczema determinants is crucial for public health initiatives.
Purpose of the Study:
- To investigate the determinants of physician-diagnosed eczema in German children and adolescents.
- To analyze associations between environmental and lifestyle factors and eczema prevalence.
Main Methods:
- Utilized data from the German Interview and Examination Survey for Children and Adolescents (KIGGS) (2003-2006).
- Included 17,641 children aged 0-17 in a nationwide cross-sectional representative survey.
- Employed univariable and multivariable logistic regression to assess exposure associations.
Main Results:
- Weighted prevalence of physician-diagnosed eczema was 13.2%.
- Parental allergies, post-birth infection, and jaundice were significant positive determinants.
- Migrant status and dog ownership showed significant inverse associations with eczema.
Conclusions:
- A family history of allergies is the most significant determinant of childhood eczema.
- Perinatal health problems are associated with eczema, emphasizing the role of early life factors.
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