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A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
Published on: November 15, 2024
Reversible magnetic resonance imaging changes associated with hypoglycemia. Case report
Shiro Yamashita1, Kenya Kawakita, Naohisa Hosomi
1Department of Neurological Surgery, Kagawa University School of Medicine, Kagawa.
Neurologia Medico-Chirurgica
|September 1, 2010
Summary
Hypoglycemia can mimic stroke symptoms, causing confusion and limb weakness. Diffusion-weighted MRI may show reversible changes in the brain, highlighting the importance of checking blood sugar levels.
Area of Science:
- Neurology
- Endocrinology
- Radiology
Background:
- Stroke is a common diagnosis for acute neurological deficits.
- Hypoglycemia can present with diverse neurological symptoms, often mimicking other conditions.
Observation:
- A 63-year-old man presented with confusion and right hemiparesis, initially suspected as stroke.
- Initial computed tomography and magnetic resonance angiography were unremarkable.
- Diffusion-weighted imaging revealed restricted diffusion in the splenium of the corpus callosum and left posterior internal capsule.
Findings:
- Blood glucose levels were critically low (23 mg/dl), confirming hypoglycemia.
- Neurological deficits resolved rapidly after intravenous glucose administration.
- Follow-up MRI showed resolution of the diffusion abnormalities.
Implications:
- Transient hypoglycemia can cause reversible diffusion-weighted imaging abnormalities, mimicking ischemic stroke.
- Prompt blood glucose measurement is crucial in patients with acute neurological deficits.
- Diffusion-weighted imaging findings in hypoglycemia should be considered in the differential diagnosis, especially when stroke is suspected but not confirmed.
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