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Two meningiomas with different histological grades in the same patient. Case report
Hakan Emmez1, Aydemir Kale, Mehmet Tönge
1Department of Neurosurgery, Gazi University Faculty of Medicine, Ankara, Turkey.
Neurologia Medico-Chirurgica
|September 1, 2010
Summary
This case report details a rare instance of a patient with two intracranial meningiomas of different grades. It highlights the importance of vigilant follow-up for all meningioma patients.
Area of Science:
- Neurosurgery
- Neuropathology
- Oncology
Background:
- Intracranial meningiomas are common primary brain tumors.
- Multicentric meningiomas, originating from multiple sites, are rare.
- Meningiomas are typically graded as I (benign), II (atypical), or III (anaplastic).
Observation:
- A 56-year-old female presented with a one-week history of speech disorder.
- Neurological and radiological assessments revealed two distinct intracranial masses.
- The tumors exhibited differing characteristics, suggesting multicentricity and varied grades.
Findings:
- Surgical resection of both meningiomas was successfully performed concurrently.
- Histopathological analysis confirmed the presence of both a meningothelial (Grade I) and an atypical (Grade II) meningioma.
- This represents an extremely rare concurrence of different-grade meningiomas within the same patient.
Implications:
- This case underscores the critical need for diligent follow-up in all meningioma patients.
- Even tumors with imaging features suggestive of benignity require ongoing monitoring due to the potential for varied pathological outcomes.
- This emphasizes the importance of considering multicentricity and differing grades in meningioma diagnosis and management.
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