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Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

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Related Experiment Video

Updated: Jun 9, 2026

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
06:54

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent

Published on: September 3, 2013

Molecular imaging with targeted contrast agents.

Marcus R Makowski1, Andrea J Wiethoff, Christian H P Jansen

  • 1Division of Imaging Sciences, King's College London, London, United Kingdom.

Topics in Magnetic Resonance Imaging : TMRI
|September 1, 2010
PubMed
Summary
This summary is machine-generated.

Molecular magnetic resonance imaging (MRI) uses targeted contrast agents for noninvasive detection of molecular changes. This review covers principles, contrast agents, MRI scanners, and applications in cardiovascular diseases.

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MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
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Area of Science:

  • Biomedical imaging
  • Molecular diagnostics
  • Cardiovascular research

Background:

  • Molecular imaging enables noninvasive detection of biological changes at the molecular level.
  • Magnetic resonance imaging (MRI) is a key modality for molecular imaging.
  • Targeted contrast agents are crucial for molecular MRI.

Purpose of the Study:

  • To review the principles of molecular MRI.
  • To discuss applications of molecular MRI in cardiovascular diseases.
  • To provide an overview of contrast agents and MRI techniques.

Main Methods:

  • Introduction to basic properties of positive and negative contrast agents.
  • Discussion of MRI scanner types and field strength effects.
  • Review of assessment and quantification of T1 and T2* relaxation time changes.

Main Results:

  • Detailed explanation of contrast agent effects on signal generation.
  • Analysis of how field strength influences contrast agent properties.
  • Overview of molecular targeting mechanisms for imaging probes.

Conclusions:

  • Molecular MRI offers advanced capabilities for cardiovascular disease characterization.
  • Understanding contrast agents and MRI physics is essential for effective molecular imaging.
  • Recent applications highlight the potential of molecular MRI in clinical settings.