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Clinical Application of Phase Angle and BIVA Z-Score Analyses in Patients Admitted to an Emergency Department with Acute Heart Failure
04:05

Clinical Application of Phase Angle and BIVA Z-Score Analyses in Patients Admitted to an Emergency Department with Acute Heart Failure

Published on: June 30, 2023

[A young man with acute, generalised oedema]

Trond Engjom1, Kristin Kampevold Larsen, Oddbjørn Hove

  • 1Gastroseksjonen, Medisinsk avdeling, Haukeland universitetssykehus, 5021 Bergen, Norway. trond.engjom@helse-bergen.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|September 1, 2010
PubMed
Abstract

Insights

Cytomegalovirus (CMV) can cause severe Ménétrier-like gastritis leading to protein loss in adults without compromised immunity. This case highlights CMV as a potential cause of this rare condition.

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Pathology

Background:

  • Ménétrier disease is a rare condition causing protein loss due to gastric foveolar hyperplasia.
  • While often idiopathic, cytomegalovirus (CMV) has been linked to self-limiting cases, particularly in children.

Observation:

  • A formerly healthy adult presented with severe hypoalbuminemia and generalized edema.
  • Endoscopic and ultrasound findings revealed gastric wall thickening consistent with Ménétrier disease.
  • Histological analysis of biopsies indicated moderate foveolar hyperplasia and suggested an infectious etiology.

Findings:

  • Intranuclear inclusion bodies, CMV-specific immunology, PCR, and special stains confirmed cytomegalovirus infection.
  • The patient experienced rapid clinical improvement following antiviral therapy.

Implications:

  • This case demonstrates that cytomegalovirus can induce severe Ménétrier-like gastritis with protein loss in non-immune-compromised adults.
  • Highlights the importance of considering infectious causes, specifically CMV, in adult patients presenting with symptoms of Ménétrier disease.

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