Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Chromosome analysis in abortion].

W Rosenkranz1, H Zierler

  • 1Institut für Medizinische Biologie und Humangenetik.

Wiener Medizinische Wochenschrift (1946)
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Novel rhodopsin mutations and genotype-phenotype correlation in patients with autosomal dominant retinitis pigmentosa.

The British journal of ophthalmology·2005
Same author

Clinical and molecular cytogenetic characterization of two patients with partial trisomy 1q41-qter: further delineation of partial trisomy 1q syndrome.

American journal of medical genetics·2001
Same author

A de novo complex chromosomal rearrangement involving chromosomes 2, 3, and 10 associated with microcephaly and early onset spasticity.

Journal of medical genetics·2001
Same author

Clinical, cytogenetic and molecular analysis of three 46,XX males.

Journal of pediatric endocrinology & metabolism : JPEM·2000
Same author

Familial mental retardation syndrome ATR-16 due to an inherited cryptic subtelomeric translocation, t(3;16)(q29;p13.3).

American journal of human genetics·2000
Same author

Mosaicism in a fragile X male including a de novo deletion in the FMR1 gene.

American journal of medical genetics·1999

Chromosome abnormalities are a common cause of miscarriage. This study identified chromosome aberrations in miscarriage tissues and in couples with recurrent pregnancy loss, highlighting their genetic basis.

Area of Science:

  • Genetics
  • Reproductive Biology
  • Cytogenetics

Context:

  • Spontaneous abortions, often termed miscarriages, are frequently linked to chromosomal abnormalities in early development.
  • Investigating these abnormalities is crucial for understanding reproductive failure.
  • Previous research indicates a significant role for genetic factors in pregnancy loss.

Purpose:

  • To investigate the prevalence of chromosome aberrations in miscarriage tissues.
  • To analyze chromosomal sets in individuals experiencing recurrent pregnancy loss.
  • To determine the genetic underpinnings of spontaneous abortions and recurrent abortions.

Summary:

  • Chromosome aberrations were detected in 15 out of 59 successfully cultivated miscarriage tissues.
  • One notable finding was the identification of trisomy 2.

Related Experiment Videos

  • Additionally, chromosomal abnormalities were found in 21 of 512 females and 12 of 474 males with a history of recurrent abortions.

    • Impact:

    • Provides critical data on the frequency of chromosomal abnormalities in miscarriages and recurrent pregnancy loss.
    • Contributes to a better understanding of the genetic etiology of reproductive failure.
    • Informs genetic counseling and potential diagnostic strategies for affected couples.